57 Results for "

Aquilaria malaccensis Lam.

" in MedChemExpress (MCE) Product Catalog:
Products (57)

57 Results for "Aquilaria malaccensis Lam." in MCE Product Catalog:

44
44 Cited Publications
Cat. No.: HY-14644
CAS No.: 541550-19-0
Purity:  99.80%
Synonyms: STA 5326; LAM-002A free base; AIT-101
Research Areas:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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44
44 Cited Publications
Cat. No.: HY-14644A
CAS No.: 870087-36-8
Purity:  99.83%
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Research Areas:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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Cat. No.: HY-129467
CAS No.: 56472-29-8
Purity:  ≥98.0%
Synonyms: 2-Hydroxyoleic acid; 2-OHOA; LAM561
Target:  

Apoptosis

Research Areas:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .
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Cat. No.: HY-N8220
CAS No.: 61828-53-3
Synonyms: Flidersiachromone
2-(2-Phenylethyl) chromone (Flidersiachromone) is a chromone derivative and antioxidant. 2-(2-Phenylethyl) chromone scavenges ABTS· + free radicals, and its derivatives exhibit diverse activities including anti-inflammatory, neuroprotective, anti-tumor, and α-glucosidase inhibitory effects. 2-(2-Phenylethyl) chromone is applicable to experimental research in fields such as inflammation-related diseases, tumors, and neurodegenerative diseases .
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Cat. No.: HY-150229
CAS No.: 2803699-70-7
Purity:  98.84%
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .
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Cat. No.: HY-N2740
CAS No.: 221257-06-3
Agalloside is a neural stem cell differentiation activator that binds to Hes1, and it is found in Aquilaria agallocha. Agalloside promotes the differentiation of neural stem cells and increases the number of neurons. Agalloside can be used in studies related to neural stem cell differentiation .
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Cat. No.: HY-N8503
CAS No.: 147821-49-6
Niazimicin can be isolated from seeds and leaves of Moringa oleifera Lam. Niazimicin is thiocarbamate compound .
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Cat. No.: HY-N3393
CAS No.: 221289-31-2
Lethedioside A is a Enhancer of split 1 (Hes1) inhibitor with an IC50 of 9.5 μM. Lethedioside A inhibits Hes1 dimer formation. Lethedioside A exhibits weak inhibition of TCF4/β-catenin complex formation. Lethedioside A inhibits nitric oxide production by activated immune cells .
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Cat. No.: HY-N4010
CAS No.: 52591-10-3
Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation .
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Cat. No.: HY-N10842
CAS No.: 88140-31-2
6-Formyllimetin is a natural product isolated from the root bark of T. asiatica LAM .
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Cat. No.: HY-N3596
CAS No.: 84575-10-0
Synonyms: Aquillochin
Cleomiscosin C (Aquillochin) can be isolated from Aquilaria agallocha. Cleomiscosin C has antioxidant activity. Cleomiscosin C inhibits LDL oxidation and free radicals generation .
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Cat. No.: HY-N10803
CAS No.: 15575-50-5
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM .
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Cat. No.: HY-164915
CAS No.: 1218932-97-8
Target:  

Bacterial

Research Areas:  

Metabolic Disease

5-InoAz is an inositol analogue used as a metabolic probe for labeling the mycobacterial cell envelope. 5-InoAz integrates into cell envelope glycolipids [phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM), and lipoarabinomannan (LAM)] .
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Cat. No.: HY-N9097
CAS No.: 122001-32-5
Niazirin is an orally active antioxidant. Niazirin can be isolated from Moringa oleifera Lam. Niazirin reduces the production levels of ROS and MDA, while increasing the levels of superoxide dismutase SOD and glutathione peroxidase GPx. Niazirin also abolishes high glucose-induced PKCζ activation and inhibits Nox4 protein expression. Niazirin exhibits excellent free radical scavenging activity. Niazirin significantly inhibits high glucose-induced proliferation of vascular smooth muscle cells. Niazirin can be used in the research of diabetic atherosclerosis .
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Cat. No.: HY-N0080
CAS No.: 28095-18-3
Synonyms: Peucedanol methyl ether
Ulopterol is a coumarin isolated from the leaves of Toddalia asiatica (L.) Lam with potent antibacterial and antifungal activities .
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Cat. No.: HY-14644B
CAS No.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
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Cat. No.: HY-N12049
CAS No.: 551-29-1
(+)-Diasyringaresinole is a lignan that can be isolated from the seeds of Aquilaria agallocha .
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Cat. No.: HY-N3419
CAS No.: 24173-71-5
Category:  

Natural Products Animals

Target:  

Others

Kobusone is a natural compound isolated form Aquilaria sinensis. kobusone can stimulate islet β-cell replication in vivo, and has the potential to be used in diabetic study .
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Cat. No.: HY-N8110
CAS No.: 626236-06-4
8-Chloro-2-(2-phenylethyl)-5,6,7-trihydroxy-5,6,7,8-tetrahydrochromone, a chromone derivative, can be found in MeOH extract of withered wood of Aquilaria sinensis .
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Cat. No.: HY-N8417
CAS No.: 142750-32-1
Buddlenoid A is a Flavonoids product that can be isolated from the herbs of Aquilaria sinensis .
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